COMPARATIVE SYNTHESIS, SPECTRAL AND ANTIMICROBIAL STUDIES OF METAL (II) COMPLEXES DERIVED FROM ASPIRIN

The objective of this research work is to compare the findings two techniques synthesis (solid state and solution based synthesis) in order know whether results are similar or not also determine if introduction metal ion increase decrease activity drug. From spectral studies, it revealed that ligand act as bidentate which coordinated central through carbonyl acid ester. elemental analysis data agreed with proposed structure complexes ratio 2:1. Bacterial test shows from compared free ligand. authors recommend application solid method provide same better result than more effective greener synthesis.